ncRNA name | hsa-miR-34a |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | human RB cell lines Y79 and SNUOT-Rb1 |
Methods | microarray |
Expression pattern | up-regulated |
Functional description | There were 17 miRNAs, which were elevated in Y79 cells than SNUOT-Rb1 cells. More than half of top 10 mRNA targets of hsa-miR-34a, hsa-miR-34c-5p, hsa-miR-124, hsa-miR-135b, hsa-miR-142-5p, and hsa-let-7i in Y79 cells were related with biological processes, which could affect the growth patterns of cells: cell adhesion, cell cycle, cell death, and cell division. |
PubMed ID | 21941147 |
Year | 2011 |
Title | Differential profiles of microRNAs in retinoblastoma cell lines of different proliferation and adherence patterns. |
Drug-related ncRNA | NO |
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